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Table 3 Differences in factors associated with tobacco, alcohol, and cannabis use in the past six months, stratified by gender identity among transgender and non-binary participants

From: Substance use patterns among a global sample of transgender and non-binary people during the COVID-19 pandemic

 

Tobacco

Alcohol

Cannabis

Non-binary

OR (95% CI)

Transfeminine

OR (95% CI)

Transmasculine

OR (95% CI)

Non-binary

OR (95% CI)

Transfeminine

OR (95% CI)

Transmasculine

OR (95% CI)

Non-binary

OR (95% CI)

Transfeminine

OR (95% CI)

Transmasculine

OR (95% CI)

Socioeconomic status

 Lower middle

1.25 (0.69, 2.25)

1.94 (0.72, 5.22)

0.51 (0.05, 4.88)

0.87 (0.47, 1.60)

1.34 (0.43, 4.20)

2.38 (0.26, 22.13)

1.06 (0.50, 2.26)

1.15 (0.31, 4.31)

5.49 (0.20, 153.81)

 Upper middle

1.24 (0.68, 2.25)

2.09 (0.72, 6.06)

0.76 (0.09, 6.48)

0.95 (0.48, 1.87)

1.34 (0.41, 4.37)

2.69 (0.15, 47.07)

1.03 (0.46, 2.31)

1.48 (0.36, 6.12)

1.37 (0.05, 37.15)

 Upper

1.18 (0.46, 3.01)

1.49 (0.41, 5.39)

0.13 (0.004, 3.99)

1.53 (0.47, 4.97)

1.04 (0.24, 4.63)

0.33 (0.01, 10.13)

0.91 (0.27, 3.06)

0.91 (0.15, 5.46)

0.92 (0.01, 81.29)

Education

 HS or trade

0.34 (0.11, 0.99)

3.27 (0.61, 17.40)

0.26 (0.01, 8.17)

0.83 (0.33, 2.11)

1.18 (0.22, 6.36)

0.26 (0.01, 9.07)

0.63 (0.20, 1.94)

0.38 (0.05, 2.80)

0.16 (0.004, 6.17)

 College

0.28 (0.10, 0.82)

1.76 (0.35, 8.81)

0.16 (0.1, 5.48)

1.40 (0.57, 3.48)

2.89 (0.59, 14.09)

0.51 (0.02, 15.07)

0.84 (0.29, 2.50)

0.55 (0.09, 3.43)

0.83 (0.04, 18.33)

Age

 25–40 years

0.87 (0.57, 1.33)

0.94 (0.45, 1.96)

0.44 (0.06, 3.13)

0.92 (0.47, 1.48)

1.17 (0.54, 2.53)

2.05 (0.19, 21.88)

1.52 (0.90, 2.58)

0.98 (0.38, 2.52)

4.13 (0.28, 61.25)

 40 + 

0.77 (0.46, 1.28)

0.42 (0.16, 1.07)

0.61 (0.09, 4.08)

0.54 (0.31, 0.93)

0.59 (0.21, 1.61)

2.64 (0.32, 22.08)

1.05 (0.54, 2.02)

0.45 (0.11, 1.75)

2.33 (0.06, 88.41)

Refused

 Health services

0.86 (0.49, 1.51)

1.39 (0.49, 3.96)

2.03 (0.07, 59.94)

0.81 (0.41, 1.59)

1.25 (0.40, 3.89)

1.53 (0.06, 38.18)

1.43 (0.67, 3.04)

1.78 (0.55, 5.77)

1.01 (0.02, 42.86)

 Police services

1.04 (0.60, 1.78)

1.24 (0.49, 3.14)

0.67 (0.04, 11.15)

0.91 (0.49, 1.68)

1.40 (0.54, 3.64)

0.91 (0.05, 16.52)

1.10 (0.50, 2.40)

0.67 (0.21, 2.07)

2.37 (0.10, 55.40)

 Disability status

1.04 (0.56, 1.95)

1.99 (0.59, 6.80)

1.24 (0.12, 12.80)

1.06 (0.45, 2.49)

1.20 (0.37, 3.94)

0.76 (0.03, 18.84)

1.76 (0.80, 3.89)

2.88 (0.83, 9.99)

3.15 (0.12, 79.82)

 Job lost due to COVID

0.75 (0.40, 1.42)

0.86 (0.25, 2.99)

0.53 (0.05, 5.82)

1.28 (0.60, 2.74)

0.62 (0.16, 2.38)

0.23 (0.01, 4.69)

1.12 (0.50, 2.53)

0.49 (0.09, 2.75)

0.96 (0.03, 28.63)

City

 Small city

0.87 (0.40, 1.89)

0.38 (0.06, 2.20)

0.55 (0.004, 71.40)

1.66 (0.76, 3.62)

11.71 (1.32, 104.06)

Omitted

0.73 (0.25, 2.17)

0.81 (0.11, 6.01)

Omitted

 Large city

1.15 (0.55, 2.38)

0.95 (0.19, 4.81)

0.41 (0.004, 42.09)

1.85 (0.88, 3.89)

3.92 (0.57, 26.72)

 

1.32 (0.49, 3.60)

0.45 (0.07, 3.15)

 

Region

 American

0.70 (0.40, 1.23)

0.65 (0.23, 1.84)

0.08 (0.01, 0.74)

2.81 (1.26, 6.26)

2.46 (0.63, 9.61)

0.51 (0.06, 4.11)

4.58 (2.50, 8.43)

2.33 (0.71, 7.67)

NA

 South East Asian

0.38 (0.25, 0.59)

0.36 (0.10, 1.33)

1.85 (0.20, 16.78)

0.49 (0.31, 0.77)

0.21 (0.05, 0.88)

0.24 (0.03, 2.07)

0.80 (0.45, 1.45)

0.20 (0.02, 2.11)

3.85 (0.37, 40.00)

 Eastern Mediterranean

1.92 (0.73, 5.01)

0.66 (0.25, 1.72)

2.28 (0.10, 51.25)

0.64 (0.27, 1.53)

0.38 (0.14, 1.01)

NA

2.67 (1.10, 6.49)

0.89 (0.26, 3.11)

9.44 (0.33, 272.96)

 Western Pacific

0.36 (0.13, 1.01)

0.20 (0.03, 1.37)

NA

0.75 (0.26, 2.18)

1.26 (0.15, 10.76)

NA

1.42 (0.43, 4.71)

NA

0.49 (0.01, 23.68)

 African

0.30 (0.03, 3.61)

0.15 (0.01, 2.07)

NA

NA

1.70 (0.15, 19.86)

NA

2.67 (0.21, 34.23)

1.14 (0.07, 18.74)

NA

  1. Statistically significant results in bold (P < 0.05)
  2. NA” refers to estimates that could not be generated due to no participants reporting the factor of interest
  3. “Omitted” refers to estimates that could not be generated due to too few participants (e.g., 4 transmasculine participants were in rural areas) such that the pooled estimates of the multiply imputed data did not converge when this variable was included. Therefore, it was removed from the assessed model
  4. Of our participants, 97 non-binary people, 28 transfeminine people, and 9 transmasculine people reported cannabis use in the last 6 months and were coded as “yes” for our binary outcome
  5. OR odds ratio, CI confidence interval, COVID-19 novel coronavirus disease 2019, EUR European Region, AMR Americas Region, SEAR Southeast Asian Region, EMR Eastern Mediterranean Region, WPR Western Pacific Region, AFR African Region